Isi ihe: Doxycycline hydrochloride

Njirimara: Ngwaahịa a bụ ìhè akwụkwọ ndụ akwụkwọ ndụ.

Omume ọgwụ:

Pharmacodynamics:Ngwaahịa a bụ ọgwụ nje tetracycline sara mbara nke nwere mmetụta antibacterial sara mbara. Nje bacteria nwere mmetụta na-agụnye nje nje gram-positive dị ka pneumococcus, streptococcus, ụfọdụ staphylococcus, anthrax, tetanus, corynebacterium na nje bacteria ndị ọzọ na-adịghị mma dị ka Escherichia coli, Pasteurella, Salmonella, Brucella na Haemophilus, Klebsiella na meliobacter. Ọ nwekwara ike igbochi Rickettsia, mycoplasma na spirochaeta ruo n'ókè ụfọdụ.

Pharmacokinetics:Ntinye ngwa ngwa, obere mmetụta nri, nnukwu bioavailability. A na-edobe ntinye ọbara dị irè ruo ogologo oge, ike nke anụ ahụ dị ike, nkesa dị obosara, ọ dịkwa mfe ịbanye na cell. Ọnụego nkesa nkịta na-apụta n'ọnọdụ kwụ ọtọ bụ ihe dịka 1.5L/kg. Ọnụego njikọ protein dị elu maka nkịta 75% ruo 86%. N'ime obere akụkụ nke chelation na-arụ ọrụ na eriri afọ, 75% nke dose nke nkịta na-ewepụ n'ụzọ dị otú a. Ọpụpụ gbasara akụrụ bụ naanị ihe dịka 25%, excretion biliary erughị 5%. Ọkara ndụ nke nkịta dị ihe dị ka awa 10 ruo 12.

Mmekọrịta ọgwụ:

(1) Mgbe ejiri sodium bicarbonate were ya, ọ nwere ike ịbawanye uru pH na afọ wee belata nnabata na ọrụ nke ngwaahịa a.

(2) Ngwaahịa a nwere ike ịmepụta ihe mgbagwoju anya na divalent na trivalent cations, wdg, ya mere, mgbe a na-ewere ya na calcium, magnesium, aluminum na antacids ndị ọzọ, ọgwụ ndị nwere ígwè ma ọ bụ mmiri ara ehi na nri ndị ọzọ, absorption ha ga-ebelata, na-akpata ya. ibelata ọgwụ ịta ahụhụ.

(3) Otu iji ọgwụ diuretics siri ike dị ka furthiamide nwere ike ime ka mmebi akụrụ ka njọ.

(4) Nwere ike igbochi mmetụta bactericidal nke penicillin na oge ịmụ nwa, kwesịrị izere otu ojiji ahụ.

Ngosipụta:

Ọrịa nke nje bacteria dị mma, nje bacteria na-adịghị mma na mycoplasma. Ọrịa iku ume (mycoplasma oyi baa, chlamydia ka oyi baa, alaka feline imi, feline calicivirus ọrịa, canine distemper). Dermatosis, usoro genitourinary, ọrịa eriri afọ, wdg.

Ojiji na usoro onunu ogwu:

Doxycycline. Maka nchịkwa ime: otu dose, 5 ~ 10mg kwa 1kg arọ ahụ maka nkịta na nwamba. A na-eji ya otu ugboro n'ụbọchị maka ụbọchị 3-5. Ma ọ bụ dị ka dọkịta nyere ya iwu. A na-atụ aro ka ị were mgbe nri na ịṅụkwu mmiri mgbe nchịkwa ọnụ gasịrị.

Ịdọ aka ná ntị:

(1) A naghị atụ aro ya maka nkịta na nwamba na-erughị izu atọ tupu a mụọ nwa, lactation, na ọnwa 1.

(2) Jiri nlezianya mee ihe na nkịta na nwamba nwere oke imeju na akụrụ arụ ọrụ.

(3) Ọ bụrụ na ịchọrọ ịṅụ ihe mgbakwunye calcium, ihe mgbakwunye ígwè, vitamin, antacids, sodium bicarbonate, wdg n'otu oge ahụ, biko ọ dịkarịa ala 2h nkeji.

(4) Amachibidoro iji diuretics na penicillin.

(5) Ejikọtara ya na phenobarbital na anticoagulant ga-emetụta ọrụ nke ibe ya.

Mmeghachi omume ọjọọ:

(1) N'ime nkịta na nwamba, mmetụta ọjọọ nke doxycycline ọnụ na-enwekarị bụ vomiting, afọ ọsịsa, na ibelata agụụ. Iji belata mmeghachi omume ọjọọ, ọnweghị mbelata dị ukwuu na nnabata ọgwụ ahụ mgbe ejiri nri.

(2) 40% nke nkịta a na-emeso nwere mmụba na enzymes metụtara ọrụ imeju (alanine aminotransferase, conglutinase bụ isi). Ihe gbasara ụlọ ọgwụ na-abawanye enzymes metụtara ọrụ imeju adịghị anya.

(3) Oral doxycycline nwere ike ịkpata stenosis esophageal na nwamba, dị ka mbadamba ụrọ, kwesịrị iji mmiri dịkarịa ala 6ml were, ọ bụghị nkụ.

(4) Ọgwụgwọ na tetracycline (karịsịa ogologo oge) nwere ike ibute oke nje bacteria na-adịghị ahụkebe ma ọ bụ fungi (ọrịa ugboro abụọ).

Ebumnuche: Naanị maka nwamba na nkịta.

Nkọwapụta: 200mg / mbadamba